Just found out I wasted 3 weeks of work, a significant amount of solvent and other reagents because the commercial starting material is not what the bottle says it is to add insult to injury what is in the bottle isn't even clean, there is at least one other thing in there.
Hilariously (not really) the only reason I determined this was because I'm making something from the literature and none of my spectra were matching close enough. Went back to the start to check and remade the first step, it produced the same wrong thing. Tried some other conditions, same deal. Finally took an NMR of the starting material today.
El Duvelle
in reply to Sam Levine • • •We usually think it's our fault when something is not working.. but sometimes it's the thing's fault!