"Moving beyond Drosophila – Jumping ants as a model species in research on gene regulation." blog.myrmecologicalnews.org/20…
"In this interview, Hua Yan, Bogdan Sieriebriennikov and Kayli Sieber highlight the key points of their paper published in Science, “Orco-dependent survival of odorant receptor neurons in ants“"
The paper:
"Orco-dependent survival of odorant receptor neurons in ants"
Sieriebriennikov et al. 2024
science.org/doi/10.1126/sciadv…
"Here, we demonstrate massive apoptosis of odorant receptor neurons (ORNs) in the mid to late stages of pupal development, possibly due to ER stress in the absence of Orco. Further bulk and single-nucle
... Show more..."Moving beyond Drosophila – Jumping ants as a model species in research on gene regulation." blog.myrmecologicalnews.org/20…
"In this interview, Hua Yan, Bogdan Sieriebriennikov and Kayli Sieber highlight the key points of their paper published in Science, “Orco-dependent survival of odorant receptor neurons in ants“"
The paper:
"Orco-dependent survival of odorant receptor neurons in ants"
Sieriebriennikov et al. 2024
science.org/doi/10.1126/sciadv…
"Here, we demonstrate massive apoptosis of odorant receptor neurons (ORNs) in the mid to late stages of pupal development, possibly due to ER stress in the absence of Orco. Further bulk and single-nucleus transcriptome analysis shows that, although most orco-expressing ORNs die in orco mutants, a small proportion of them survive: They express ionotropic receptor (Ir) genes that form IR complexes. In addition, we found that some Or genes are expressed in mechanosensory neurons and nonneuronal cells, possibly due to leaky regulation from nearby non-Or genes."
#ants #genetics #neuroscience #olfaction
Olfaction is essential for complex social behavior in insects. To discriminate complex social cues, ants evolved an expanded number of odorant receptors (Or) genes strategically located in the antennae. Mutations in the obligate odorant co-receptor
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