"The article showcases the evidence that mitochondrial dysfunction is a major aftermath associated with SARS-CoV-2 infection as the impaired Mitochondria leads to an accumulation of reactive oxygen species (ROS), triggering endothelial dysfunction, and leading to the passage of harmful molecules across the BBB."
[1]guess it's time for a thread of excerpts!
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[1] nature.com/articles/s41598-024… via zeroes.ca/explore/links
#COVID #COVID19 #SARSCoV2 #pandemic #COVIDIsNotOver #LongCOVID
Omics-based analysis of mitochondrial dysfunction and BBB integrity in post-COVID-19 sequelae - Scientific Reports
Scientific Reports - Omics-based analysis of mitochondrial dysfunction and BBB integrity in post-COVID-19 sequelaeNature
This entry was edited (1 week ago)
datum (n=1)
in reply to datum (n=1) • • •How long is the current list of Long COVID suspects?
"Several interconnected factors contribute to the development of various health issues associated with SARS-CoV-2. These factors include the presence of spike proteins in cells and tissues, dysregulated immune systems, reactivation of latent pathogens such as human herpesvirus 6 (HHV-6) and Epstein-Barr virus (EBV), changes in the microbiota and virome caused by SARS-CoV-2, autoimmune responses triggered by self-antibodies, microvascular clotting that leads to endothelial dysfunction, and disruptions in the brainstem and/or vagus nerve2."
2/🧵
nature.com/articles/s41598-024…
#COVID #COVID19 #SARSCoV2 #pandemic #COVIDIsNotOver #LongCOVID
Omics-based analysis of mitochondrial dysfunction and BBB integrity in post-COVID-19 sequelae - Scientific Reports
Naturedatum (n=1)
in reply to datum (n=1) • • •What's the outlook for the brain, long term?
"the risk of cognitive impairment (brain fog), seizures, dementia, psychosis, and other neurocognitive conditions persisted even for 2 years6. Furthermore, recent research by Kumari A. et al., has demonstrated a strong association between COVID-19 and neurodegeneration, raising the possibility that COVID-19 could play a part in the emergence of neurodegenerative illnesses in the future7."
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nature.com/articles/s41598-024…
#COVID #COVID19 #SARSCoV2 #pandemic #COVIDIsNotOver #LongCOVID
Omics-based analysis of mitochondrial dysfunction and BBB integrity in post-COVID-19 sequelae - Scientific Reports
Nature